kallisto | bustools
基于伪比对的快速单细胞 RNA-seq 预处理流程,利用 kallisto 索引和 bustools 流式处理实现轻量级定量。 该方法内存占用极低,处理速度快,支持多种单细胞平台,是大规模单细胞数据预处理的高效替代方案。
| Property | Value |
|---|---|
| Purpose | 快速轻量的单细胞 RNA-seq 数据预处理 |
| Time Complexity | O(n * k) |
| Space Complexity | O(g) |
| Year | 2021 |
| Difficulty | Intermediate |
| Languages | C++ |
| Category | Single-Cell Genomics |
Complexity Analysis
- Time Complexity:
O(n * k) - Space Complexity:
O(g)
Performance Insight: The time complexity of this algorithm is polynomial.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
Cell Ranger · STARsolo · Alevin