A curated collection of 200+ bioinformatics algorithms with complexity analysis, implementation links, and comprehensive documentation in English and Chinese. https://lessup.github.io/awesome-bioinfo-algorithms/ LessUp Communityhttps://github.com/LessUp/awesome-bioinfo-algorithmszh Wed, 22 Apr 2026 03:04:34 -0000 Wed, 22 Apr 2026 03:04:34 -0000 1440 MkDocs RSS plugin - v1.19.0 None https://lessup.github.io/awesome-bioinfo-algorithms/ <h1>变异检测</h1> <blockquote> <p>检测基因组变异的算法</p> </blockquote> <p><strong>14</strong> 个算法收录于该分类。</p> <h2>单核苷酸变异 (SNV Detection)</h2> <p><em>检测单核苷酸变异和小型插入缺失</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><tr... https://lessup.github.io/awesome-bioinfo-algorithms/categories/variant-calling/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/variant-calling/ <h1>空间组学</h1> <blockquote> <p>保留空间信息的组学数据分析算法</p> </blockquote> <p><strong>10</strong> 个算法收录于该分类。</p> <h2>空间转录组学 (Spatial Transcriptomics)</h2> <p><em>空间分辨的基因表达分析方法</em></p> <div class="aba-table-container"> <table class="aba-table... https://lessup.github.io/awesome-bioinfo-algorithms/categories/spatial-omics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/spatial-omics/ <h1>单细胞基因组学</h1> <blockquote> <p>单细胞水平的基因组和转录组分析算法</p> </blockquote> <p><strong>15</strong> 个算法收录于该分类。</p> <h2>数据预处理 (Preprocessing)</h2> <p><em>单细胞数据的质控、标准化和预处理</em></p> <div class="aba-table-container"> <table class="aba-table"> ... https://lessup.github.io/awesome-bioinfo-algorithms/categories/single-cell/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/single-cell/ <h1>序列比对</h1> <blockquote> <p>用于比较和对齐生物序列的算法</p> </blockquote> <p><strong>19</strong> 个算法收录于该分类。</p> <h2>双序列比对 (Pairwise Alignment)</h2> <p><em>两条序列之间的比对算法</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead... https://lessup.github.io/awesome-bioinfo-algorithms/categories/sequence-alignment/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/sequence-alignment/ <h1>蛋白质结构预测</h1> <blockquote> <p>预测蛋白质三维结构的算法</p> </blockquote> <p><strong>14</strong> 个算法收录于该分类。</p> <h2>从头预测 (Ab Initio Prediction)</h2> <p><em>基于序列信息的从头结构预测</em></p> <div class="aba-table-container"> <table class="aba-table"> <t... https://lessup.github.io/awesome-bioinfo-algorithms/categories/protein-structure/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/protein-structure/ <h1>蛋白质语言模型</h1> <blockquote> <p>基于大规模预训练模型的蛋白质分析算法</p> </blockquote> <p><strong>10</strong> 个算法收录于该分类。</p> <h2>蛋白质语言模型预训练 (Protein Language Model Pretraining)</h2> <p><em>蛋白质序列的语言模型和表征学习方法</em></p> <p>&lt;div class="aba-table-container"...</p> https://lessup.github.io/awesome-bioinfo-algorithms/categories/protein-language-model/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/protein-language-model/ <h1>群体遗传学</h1> <blockquote> <p>分析群体遗传结构和进化的算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>主成分与群体结构 (PCA &amp; Population Structure)</h2> <p><em>降维和群体结构推断方法</em></p> <div class="aba-table-container"> <table class="aba-ta... https://lessup.github.io/awesome-bioinfo-algorithms/categories/population-genetics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/population-genetics/ <h1>系统发育分析</h1> <blockquote> <p>构建和分析进化树的算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>距离法 (Distance Methods)</h2> <p><em>基于距离矩阵的建树方法</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><tr>... https://lessup.github.io/awesome-bioinfo-algorithms/categories/phylogenetics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/phylogenetics/ <h1>宏基因组学</h1> <blockquote> <p>微生物群落的基因组分析算法</p> </blockquote> <p><strong>14</strong> 个算法收录于该分类。</p> <h2>物种分类 (Taxonomic Profiling)</h2> <p><em>微生物物种组成鉴定</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><... https://lessup.github.io/awesome-bioinfo-algorithms/categories/metagenomics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/metagenomics/ <h1>图基因组学</h1> <blockquote> <p>基于图结构表示和分析基因组的算法</p> </blockquote> <p><strong>9</strong> 个算法收录于该分类。</p> <h2>泛基因组 (Pangenome)</h2> <p><em>构建和分析泛基因组图的方法</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><tr><... https://lessup.github.io/awesome-bioinfo-algorithms/categories/graph-genomics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/graph-genomics/ <h1>基因预测</h1> <blockquote> <p>基因结构预测和基因组注释算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>真核基因预测 (Eukaryotic Gene Prediction)</h2> <p><em>真核生物基因结构预测</em></p> <div class="aba-table-container"> <table class="aba-table"... https://lessup.github.io/awesome-bioinfo-algorithms/categories/gene-prediction/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/gene-prediction/ <h1>功能注释</h1> <blockquote> <p>预测基因和蛋白质功能的算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>同源性方法 (Homology-Based)</h2> <p><em>基于序列同源性的功能推断</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><tr... https://lessup.github.io/awesome-bioinfo-algorithms/categories/functional-annotation/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/functional-annotation/ <h1>基因表达分析</h1> <blockquote> <p>分析基因表达水平的算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>表达定量 (Expression Quantification)</h2> <p><em>转录本和基因水平的表达量估计</em></p> <div class="aba-table-container"> <table class="aba-table"... https://lessup.github.io/awesome-bioinfo-algorithms/categories/expression-analysis/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/expression-analysis/ <h1>表观基因组学</h1> <blockquote> <p>分析表观遗传修饰的算法</p> </blockquote> <p><strong>12</strong> 个算法收录于该分类。</p> <h2>ChIP-seq 分析 (ChIP-seq Analysis)</h2> <p><em>染色质免疫共沉淀测序分析</em></p> <div class="aba-table-container"> <table class="aba-table"> <... https://lessup.github.io/awesome-bioinfo-algorithms/categories/epigenomics/ Wed, 22 Apr 2026 03:04:38 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/epigenomics/ <h1>数据压缩</h1> <blockquote> <p>压缩生物信息学数据的算法</p> </blockquote> <p><strong>10</strong> 个算法收录于该分类。</p> <h2>通用压缩 (General Compression)</h2> <p><em>通用数据压缩格式</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><tr>... https://lessup.github.io/awesome-bioinfo-algorithms/categories/data-compression/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/data-compression/ <h1>序列组装</h1> <blockquote> <p>从短读段重建完整序列的算法</p> </blockquote> <p><strong>14</strong> 个算法收录于该分类。</p> <h2>从头组装 (De Novo Assembly)</h2> <p><em>不依赖参考序列的组装方法</em></p> <div class="aba-table-container"> <table class="aba-table"> <thead><t... https://lessup.github.io/awesome-bioinfo-algorithms/categories/assembly/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/assembly/ <h1>分类总览</h1> <p>共 <strong>16</strong> 个研究方向，按算法数量排序。</p> <div class="aba-bento-grid"> <a class="aba-bento-card aba-animate aba-animate-delay-0" href="sequence-alignment/"> <div cla... https://lessup.github.io/awesome-bioinfo-algorithms/categories/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/categories/ <h1>Wtdbg2</h1> <!-- Detail Hero --> <div class="aba-detail-hero"> <div class="aba-detail-header"> <div class="aba-detail-badges"> <span class="aba-bad... https://lessup.github.io/awesome-bioinfo-algorithms/algorithms/wtdbg2/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/algorithms/wtdbg2/ <h1>WFA2-lib</h1> <!-- Detail Hero --> <div class="aba-detail-hero"> <div class="aba-detail-header"> <div class="aba-detail-badges"> <span class="aba-b... https://lessup.github.io/awesome-bioinfo-algorithms/algorithms/wfa2/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/algorithms/wfa2/ <h1>VG (Variation Graph)</h1> <!-- Detail Hero --> <div class="aba-detail-hero"> <div class="aba-detail-header"> <div class="aba-detail-badges"> <span ... https://lessup.github.io/awesome-bioinfo-algorithms/algorithms/vg-toolkit/ Wed, 22 Apr 2026 03:04:37 +0000 Awesome Bioinformatics Algorithmshttps://lessup.github.io/awesome-bioinfo-algorithms/algorithms/vg-toolkit/