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基于配体-受体相互作用数据库推断细胞间通讯的方法,可从单细胞或空间转录组 数据中识别显著的细胞通讯通路。该方法整合了信号通路信息,提供通讯网络的 可视化和功能推断。

PropertyValue
Purpose基于配体-受体互作的细胞通讯推断
Time ComplexityO(c^2 * g)
Space ComplexityO(c^2)
Year2021
DifficultyIntermediate
LanguagesR
CategorySpatial Omics

Complexity Analysis

  • Time Complexity: O(c^2 * g)
  • Space Complexity: O(c^2)

Performance Insight: The time complexity of this algorithm is polynomial.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

Literature & Implementation

CellPhoneDB · NicheNet · squidpy

Tags

cell-communication ligand-receptor signaling network

Released under the MIT License.