CellChat
基于配体-受体相互作用数据库推断细胞间通讯的方法,可从单细胞或空间转录组 数据中识别显著的细胞通讯通路。该方法整合了信号通路信息,提供通讯网络的 可视化和功能推断。
| Property | Value |
|---|---|
| Purpose | 基于配体-受体互作的细胞通讯推断 |
| Time Complexity | O(c^2 * g) |
| Space Complexity | O(c^2) |
| Year | 2021 |
| Difficulty | Intermediate |
| Languages | R |
| Category | Spatial Omics |
Complexity Analysis
- Time Complexity:
O(c^2 * g) - Space Complexity:
O(c^2)
Performance Insight: The time complexity of this algorithm is polynomial.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
CellPhoneDB · NicheNet · squidpy