Delly
基于分裂读段和双端读段信号的结构变异检测算法，能够发现缺失、重复、倒位和易位等大规模基因组变异。 该方法结合多种信号源提高检测灵敏度，是结构变异检测领域的代表性工具之一。
| Property | Value |
|---|---|
| Purpose | 检测基因组结构变异（缺失、重复、倒位、易位） |
| Time Complexity | O(n * c) |
| Space Complexity | O(n) |
| Year | 2012 |
| Category | Variant Calling |
Complexity Analysis
- Time Complexity:
O(n * c) - Space Complexity:
O(n)
Performance Insight: The time complexity of this algorithm is polynomial. Linear space can often be reduced by constant factors via sliding-window techniques.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
Manta · LUMPY · GRIDSS