DIAMOND
基于双索引策略的超快速蛋白质和核苷酸序列比对工具,比 BLAST 快数万倍。 该方法在保持高灵敏度的同时大幅提升搜索速度,适用于大规模宏基因组学和蛋白质组学分析。
| Property | Value |
|---|---|
| Purpose | 超快速蛋白质和核苷酸序列比对 |
| Time Complexity | O(mn) |
| Space Complexity | O(m + n) |
| Year | 2015 |
| Difficulty | Intermediate |
| Languages | C++ |
| Category | Sequence Alignment |
Complexity Analysis
- Time Complexity:
O(mn) - Space Complexity:
O(m + n)
Performance Insight: The time complexity of this algorithm is quadratic matrix (O(mn)), SIMD acceleration or approximate methods are advised when m, n exceed 10⁴.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
BLAST · MMseqs2 · RAPSearch2