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DIAMOND

基于双索引策略的超快速蛋白质和核苷酸序列比对工具,比 BLAST 快数万倍。 该方法在保持高灵敏度的同时大幅提升搜索速度,适用于大规模宏基因组学和蛋白质组学分析。

PropertyValue
Purpose超快速蛋白质和核苷酸序列比对
Time ComplexityO(mn)
Space ComplexityO(m + n)
Year2015
DifficultyIntermediate
LanguagesC++
CategorySequence Alignment

Complexity Analysis

  • Time Complexity: O(mn)
  • Space Complexity: O(m + n)

Performance Insight: The time complexity of this algorithm is quadratic matrix (O(mn)), SIMD acceleration or approximate methods are advised when m, n exceed 10⁴.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

Literature & Implementation

BLAST · MMseqs2 · RAPSearch2

Tags

heuristic protein-alignment fast ultra-fast

Released under the MIT License.