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HiFiBD

专为 PacBio HiFi 数据设计的泛基因组图分型方法,利用图结构中的变异信息 提高低频变异的检测灵敏度。该方法可直接在泛基因组图上进行比对和分型。

PropertyValue
Purpose泛基因组图上的 HiFi 数据分型
Time ComplexityO(n * d)
Space ComplexityO(n)
Year2022
DifficultyAdvanced
LanguagesC++
CategoryGraph Genomics

Complexity Analysis

  • Time Complexity: O(n * d)
  • Space Complexity: O(n)

Performance Insight: The time complexity of this algorithm is polynomial. Linear space can often be reduced by constant factors via sliding-window techniques.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

VG · Minigraph · GraphAligner

Tags

variation-graph hifi genotyping pangenome

Released under the MIT License.