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MUSCLE

基于迭代优化的多序列比对算法,通过多轮渐进比对和精化步骤提高比对质量。 该方法在速度和准确性之间取得了良好平衡,适用于中等规模的序列集合。

PropertyValue
Purpose高精度多序列比对
Time ComplexityO(n^2 * L)
Space ComplexityO(n * L)
Year2004
CategorySequence Alignment

Complexity Analysis

  • Time Complexity: O(n^2 * L)
  • Space Complexity: O(n * L)

Performance Insight: The time complexity of this algorithm is polynomial.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

Literature & Implementation

MAFFT · Clustal Omega · PROBCONS

Tags

multiple-alignment iterative refinement classic

Released under the MIT License.