Strelka2
快速准确的体细胞和生殖系小型变异检测工具，使用分层混合模型提高检测灵敏度。 该方法速度极快，能在数小时内完成全基因组变异检测，广泛用于癌症基因组学研究。
| Property | Value |
|---|---|
| Purpose | 快速体细胞和生殖系变异检测 |
| Time Complexity | O(n * r) |
| Space Complexity | O(r) |
| Year | 2018 |
| Category | Variant Calling |
Complexity Analysis
- Time Complexity:
O(n * r) - Space Complexity:
O(r)
Performance Insight: The time complexity of this algorithm is polynomial.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
Mutect2 · VarScan2 · GATK