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Cactus

基于祖先引导的全基因组比对和泛基因组图构建方法,使用 progressive cactus 算法处理多物种间的共线性关系。该方法可构建大规模的全基因组比对和泛基因组 参考图。

PropertyValue
Purpose多物种全基因组比对和泛基因组构建
Time ComplexityO(n^2 * k)
Space ComplexityO(n * k)
Year2011
DifficultyAdvanced
LanguagesC, Python
CategoryGraph Genomics

Complexity Analysis

  • Time Complexity: O(n^2 * k)
  • Space Complexity: O(n * k)

Performance Insight: The time complexity of this algorithm is polynomial.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

Literature & Implementation

Minigraph · PGGB · Mauve

Tags

pangenome alignment progressive multi-species

Released under the MIT License.