Minimap2
通用的序列比对工具,支持长读段(PacBio/ONT)和短读段的快速比对。 该方法使用最小化子(minimizer)索引实现超快速比对,是长读段数据分析的首选工具。
| Property | Value |
|---|---|
| Purpose | 长读段和短读段的通用快速比对 |
| Time Complexity | O(n) |
| Space Complexity | O(n) |
| Year | 2018 |
| Category | Sequence Alignment |
Complexity Analysis
- Time Complexity:
O(n) - Space Complexity:
O(n)
Performance Insight: The time complexity of this algorithm is linear (O(n)), scales linearly to TB-scale data and is suitable for streaming pipelines. Linear space can often be reduced by constant factors via sliding-window techniques.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
BWA · NGMLR · Winnowmap