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Minimap2

通用的序列比对工具,支持长读段(PacBio/ONT)和短读段的快速比对。 该方法使用最小化子(minimizer)索引实现超快速比对,是长读段数据分析的首选工具。

PropertyValue
Purpose长读段和短读段的通用快速比对
Time ComplexityO(n)
Space ComplexityO(n)
Year2018
CategorySequence Alignment

Complexity Analysis

  • Time Complexity: O(n)
  • Space Complexity: O(n)

Performance Insight: The time complexity of this algorithm is linear (O(n)), scales linearly to TB-scale data and is suitable for streaming pipelines. Linear space can often be reduced by constant factors via sliding-window techniques.

Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.

Literature & Implementation

BWA · NGMLR · Winnowmap

Tags

minimizer long-read versatile fast

Released under the MIT License.