PfamScan
基于 Pfam 蛋白家族数据库和 HMM profile 的结构域注释工具，可识别蛋白序列中的保守结构域与功能模块。 该方法常与 HMMER 联合使用，为蛋白功能推断、家族分类和结构域组合分析提供标准化结果。
| Property | Value |
|---|---|
| Purpose | 基于 Pfam profile 进行蛋白结构域识别与功能注释 |
| Time Complexity | O(mn) |
| Space Complexity | O(m) |
| Year | 2011 |
| Category | Functional Annotation |
Complexity Analysis
- Time Complexity:
O(mn) - Space Complexity:
O(m)
Performance Insight: The time complexity of this algorithm is quadratic matrix (O(mn)), SIMD acceleration or approximate methods are advised when m, n exceed 10⁴.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
HMMER · InterProScan · SMART