RagTag
基于参考基因组进行 scaffold 排序、定向和纠错的组装改进工具，常用于提升草图组装的连续性和完整度。 该方法能够快速将 contig 锚定到近缘参考序列，为植物和动物基因组装配提供高效的参考引导整理能力。
| Property | Value |
|---|---|
| Purpose | 基于参考基因组改进 scaffold 排序与定向 |
| Time Complexity | O(n log n) |
| Space Complexity | O(n) |
| Year | 2022 |
| Category | Sequence Assembly |
Complexity Analysis
- Time Complexity:
O(n log n) - Space Complexity:
O(n)
Performance Insight: The time complexity of this algorithm is quasi-linear (n log n), balancing practical efficiency with theoretical near-optimality. Linear space can often be reduced by constant factors via sliding-window techniques.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
Ragout · RaGOO · Minimap2
Tags
reference-based scaffolding assembly-polishing genome-finishing