SvABA
基于局部组装的结构变异和体细胞突变检测工具，能够同时识别生殖系和体细胞的结构变异事件。 该方法通过断点图和单倍型组装精确定位变异断点，适用于癌症基因组学中的复杂变异检测。
| Property | Value |
|---|---|
| Purpose | 基于局部组装的结构变异和体细胞突变检测 |
| Time Complexity | O(n * c) |
| Space Complexity | O(c) |
| Year | 2016 |
| Category | Variant Calling |
Complexity Analysis
- Time Complexity:
O(n * c) - Space Complexity:
O(c)
Performance Insight: The time complexity of this algorithm is polynomial.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
Manta · GRIDSS · Delly