Orione
利用参考辅助压缩的 FASTQ 和 SAM 格式压缩工具，将读段比对到参考序列后仅存储差异信息。该方法在有高质量参考基因组时压缩效果极佳。
| Property | Value |
|---|---|
| Purpose | 参考辅助的 FASTQ/SAM 压缩 |
| Time Complexity | O(n) |
| Space Complexity | O(1) |
| Year | 2015 |
| Difficulty | Intermediate |
| Languages | C |
| Category | Data Compression |
Complexity Analysis
- Time Complexity:
O(n) - Space Complexity:
O(1)
Performance Insight: The time complexity of this algorithm is linear (O(n)), scales linearly to TB-scale data and is suitable for streaming pipelines. Space overhead is minimal, making it suitable for memory-constrained or streaming environments.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
Related Tools
CRAM · Genozip · Spring