Salmon
基于选择性比对的高速转录本定量工具，使用轻量级比对和在线 EM 算法估计转录本丰度。 该方法速度极快且内存占用低，能够校正 GC 含量偏差和序列特异性偏差。
| Property | Value |
|---|---|
| Purpose | 快速准确的转录本定量 |
| Time Complexity | O(n) |
| Space Complexity | O(t) |
| Year | 2017 |
| Category | Gene Expression Analysis |
Complexity Analysis
- Time Complexity:
O(n) - Space Complexity:
O(t)
Performance Insight: The time complexity of this algorithm is linear (O(n)), scales linearly to TB-scale data and is suitable for streaming pipelines.
Note: Complexity analysis is based on theoretical models. Actual runtime is affected by input scale, hardware, and implementation optimizations. Benchmark for your specific workload.
Literature & Implementation
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Kallisto · RSEM · Sailfish